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PubMed · 588737

[Modeling experimental pollinosis].

A D Ado·T A Lukmanova·T A Alekseeva·T A Avdeeva
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Abstract

Experimental pollinosis was modelled on guinea pigs. The animals were placed in a cell in which an allergen-water-dialyzed extract of ambrosia pollen was dispersed by means of coaxial pulveriser. Homocytotropic antibodies serving as indices of animal sensitization to the specific allergen formed in guinea pigs as a result of aerosol sensitization. Sensitization of the animals to the ambrosia allergen was accompanied by an increase of sensitivity of the broncho-pulmonary apparatus and was characterized by the bronchospastic reaction in resolving inhalation or inrtavenous injection of a specific allergen.

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AerosolsAllergensAnimalsCell ExtractsDisease Models, AnimalGuinea PigsPassive Cutaneous AnaphylaxisPollenRespirationRhinitis, Allergic, SeasonalEnglish AbstractJournal Article

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A D Ado, T A Lukmanova, T A Alekseeva, T A Avdeeva. 1977. [Modeling experimental pollinosis].. https://pubmed.ncbi.nlm.nih.gov/588737/

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