A computerized scanner to quantify atherosclerosis.

M J Legg; B S Gow; M Hodgekiss

doi:10.1016/0021-9150(80)90243-9

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A computerized scanner to quantify atherosclerosis.

M J Legg·B S Gow·M Hodgekiss

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Abstract

A method is described for the quantitation of atherosclerotic lesion after excision and staining of the vessel. Essentially the device consists of a microscope with a computer-controlled stage which moves a photographic negative image over a square beam (o.1 mm sides) of light. At each translation-step of the stage a transmittance reading is taken using a photomultiplier tube for detection. The computer stores topographical values (typically around 6,000) and, by setting a threshold, can determine the fractional area of artery which is diseased.

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Animals Aorta Arteries Arteriosclerosis Computers Rabbits Staining and Labeling Journal Article Research Support, Non-U.S. Gov't

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M J Legg, B S Gow, M Hodgekiss. 1980. A computerized scanner to quantify atherosclerosis.. https://doi.org/10.1016/0021-9150(80)90243-9

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