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PubMed · 6214671

Prosthetic replacement for the thoracic vena cava: an experimental study.

A C Fiore·J W Brown·R S Cromartie·L C Ofstein·P S Peigh·N S Sears·W P Deschner·H King
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Abstract

The superior vena cava (SVC) and thoracic inferior vena cava (IVC) were replaced in 46 dogs with autologous vein, knitted Dacron, glutaraldehyde-fixed porcine pericardium, unsupported polytetrafluorethylene (PTFE), and externally stented PTFE. After 30 days, patency rates were determined by contrast venography and were 100%, 9%, 50%, 75%, and 100%, respectively. The patency rates of Dacron and glutaraldehyde-fixed pericardium are considered unacceptable when compared to autologous vein (p less than 0.05). Stented PTFE exhibited a patency rate equal to that of autologous vein at 30 days, minimal graft reaction, excellent incorporation by host fibroblasts, and a smooth neointima. The external spiral support added to PTFE enchanced the thromboresistance of this graft in the thoracic venous system. Long-term follow-up is required to determine if the stented PTFE prosthesis remains comparable to autologous vein as a venous conduit.

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AnimalsBioprosthesisBlood Vessel ProsthesisDogsGraft SurvivalPolyethylene TerephthalatesPolytetrafluoroethyleneVena Cava, InferiorVena Cava, SuperiorJournal Article

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A C Fiore, J W Brown, R S Cromartie, L C Ofstein, P S Peigh, N S Sears, W P Deschner, H King. 1982. Prosthetic replacement for the thoracic vena cava: an experimental study.. https://pubmed.ncbi.nlm.nih.gov/6214671/

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