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PubMed · 6216794

[Decrease in the number of SE-rosettes by means of sera containing immune complexes].

I Lohrisch·J Schaller·H Sauer·K Drössler
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Abstract

The number of peripheral blood lymphocytes (PBL) rosetting with sheep erythrocytes (SE-rosettes) was significantly decreased by preincubation with both sera containing immune complexes (IC) and prepared antigen-antibody complexes. However, this effect of decrease in rosetting ability of PBL could be completely reversed by a second incubation of the cells for 30 minutes at 37 degrees C in IC-free medium. The immune complexes and antigen-antibody complexes respectively could bind reversibly to T cells via Fc-receptors and subsequently interfere with the T cell receptors for SE by steric hindrance.

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AnimalsAntigen-Antibody ComplexBloodCattleDogsGuinea PigsHumansImmune ToleranceImmunoglobulin GImmunoglobulin MReceptors, FcRosette FormationSheepEnglish AbstractJournal Article

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I Lohrisch, J Schaller, H Sauer, K Drössler. 1982. [Decrease in the number of SE-rosettes by means of sera containing immune complexes].. https://pubmed.ncbi.nlm.nih.gov/6216794/

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