[Preparative isolation of alpha 2-macroglobulin, transferrin, albumin and study of their nonspecific gamma-inhibitory activity].

M Kh Saiatov; R U Beĭsembaeva

PubMed · 64024

[Preparative isolation of alpha 2-macroglobulin, transferrin, albumin and study of their nonspecific gamma-inhibitory activity].

Abstract

Profiles of distribution of non-specific gamma-inhibitors of influenza A2/Victoria/35/72 in donkey and horse sera were established by gel chromatography in Sephadex G-200. High and low molecular inhibitors were found in 19S and 4S serum fractions. Highly purified preparations of a2-macroglobulin, transferrine and albumin were isolated by a combination of methods of salt precipitation, gel chromatography on Sephadex G-100, G-200 and ion exchange on DEAE-Sephadex A-50. Heating sera resulted in a considerable increase of the antiviral activity of a2-macroglobulin and transferrine and a reduction of albumin activity.

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Animals Antiviral Agents Horses Hot Temperature Immune Sera Influenza A virus Methods Perissodactyla Serum Albumin Transferrin alpha-Macroglobulins English Abstract Journal Article

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M Kh Saiatov, R U Beĭsembaeva. [Preparative isolation of alpha 2-macroglobulin, transferrin, albumin and study of their nonspecific gamma-inhibitory activity].. https://pubmed.ncbi.nlm.nih.gov/64024/

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