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PubMed · 6516632

[Fetomaternal macrotransfusion with severe fetal anemia].

V Briese·R Plesse
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Abstract

A fetomaternal macrotransfusion endangers fetal life. This report describes a fetomaternal macrotransfusion of about 300 ml blood. Ante partum and intra partum monitoring showed a mild fetal tachycardia. After spontaneous delivery the newborn was severe anemic and has a mild hepatosplenomegaly and edema. The diagnosis of fetomaternal macrotransfusion was made by Kleihauer-Betke-Test with maternal blood.

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Anemia, NeonatalBilirubinElectrocardiographyFemaleFetal BloodFetal HeartFetal MonitoringFetomaternal TransfusionHematocritHemoglobinometryHumansInfant, NewbornPregnancyTachycardiaEnglish AbstractJournal Article

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V Briese, R Plesse. 1984. [Fetomaternal macrotransfusion with severe fetal anemia].. https://pubmed.ncbi.nlm.nih.gov/6516632/

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PubMed2003

Efficacy, recovery, and safety of RBCs from autologous placental blood: clinical experience in 52 newborns.

BACKGROUND: In the present study, the efficacy, recovery, and safety of RBCs from autologous placental blood (PB-RBCs) were investigated. STUDY DESIGN AND METHODS: A total of 52 newborns received transfusion with PB-RBCs. The number of newborns requiring no additional allogeneic RBCs was calculated. In 22 of these 52 neonates with a birth weight of 1000 to 2500 g, vital measures were performed during transfusion, and serum potassium levels were measured up to 3 days after transfusion. The results were compared with those of a matched control group given allogeneic RBC transfusions. RESULTS: All neonates of the study group with a birth weight of less than 1000 g, but only 59 percent those with a birth weight of 1000 to 2500 g and 58 percent of those requiring surgery directly after delivery needed allogeneic transfusions in addition to PB-RBCs. The mean Hb increase after RBC transfusion of 10 mL per kg of body weight was 3 g per dL per kg of body weight in both groups; the Hb decrease was accelerated in the placental blood group (0.32 vs. 0.24 g/dL/day; p < 0.05). There were no intergroup differences in the vital parameters. CONCLUSION: Our results show no difference in efficacy and safety between PB-RBC transfusion and allogeneic RBC transfusion. According to well-defined criteria, 40 percent of anemic neonates can be supported by autologous placental blood transfusions alone.

Anemia, Neonatal↗