Pulmonary function studies in diffuse pulmonary North American blastomycosis.

Abstract

Detailed pulmonary function studies were performed on 2 patients with diffuse pulmonary North American blastomycosis before and after therapy. Our studies showed a significant increase in lung restriction, stiffness, and small airways obstruction, which completely resolved with therapy. We conclude that adequate therapy, even in the presence of extensive disease, results in both clinical and physiologic recovery.