A computer method for the comparison or the quantitative similarity between normal and abnormal collagen or between sequence data and experimental data.

M Tzaphlidou; R A Hardcastle

doi:10.1016/0020-7101(84)90023-0

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A computer method for the comparison or the quantitative similarity between normal and abnormal collagen or between sequence data and experimental data.

M Tzaphlidou·R A Hardcastle

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Abstract

In this paper, a method is described to correlate collagen structural data obtained by electron microscopy with chemical sequence data, or to compare two experimental sets of data. In this respect, collagen provides a valuable model system, firstly for studying the chemical basis of ultrastructure and the mechanisms of various treatments on a protein, and secondly for detecting and locating the alterations in collagen fibril structure produced by a collagen disorder.

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Amino Acid Sequence Collagen Collagen Diseases Computers Humans Microscopy, Electron Protein Conformation Comparative Study Journal Article Research Support, Non-U.S. Gov't

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M Tzaphlidou, R A Hardcastle. A computer method for the comparison or the quantitative similarity between normal and abnormal collagen or between sequence data and experimental data.. https://doi.org/10.1016/0020-7101(84)90023-0

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