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PubMed · 696799

Morphologic abnormalities in potassium-deficient dogs.

C L Tate·W J Bagdon·D L Bokelman
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Abstract

Potassium deficiency was produced in 16 dogs by means of a diet containing less than 0.03% potassium. Decreases in serum potassium were first observed after 3 weeks. Morphologic changes occurred only in heart, skeletal muscle, and kidney. Focal myocardial necrosis was observed in 6 of 16 deficient dogs, and skeletal muscle degeneration and necrosis were observed in 14 of 16 deficient dogs. A complex nephropathy consisting primarily of epithelial hypertrophy and hyperplasia in the collecting tubules of the inner stripe of the outer medulla occurred in all the deficient dogs.

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AnimalsDogsFemaleHyperplasiaKidneyKidney CortexKidney MedullaKidney TubulesMaleMusclesMyocardiumPotassiumPotassium DeficiencyVacuolesJournal Article

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C L Tate, W J Bagdon, D L Bokelman. 1978. Morphologic abnormalities in potassium-deficient dogs.. https://pubmed.ncbi.nlm.nih.gov/696799/

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