Prostaglandins and renal function.

J C McGiff; D A Terragno; N A Terragno

doi:10.1159/000401652

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Prostaglandins and renal function.

J C McGiff·D A Terragno·N A Terragno

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Abstract

Prostaglandins modulate the effects of vasoactive hormones by attenuating the renal actions of the renin-angiotensin system and contributing to and, perhaps, mediating some of those of the kallikrein-kinin system. A prostaglandin mechanism participates in the regulation of renin and erythropoietin release. When renal function is compromised, the circulation to the kidney is sustained by a major prostaglandin component withdrawal of which results in significant hemodynamic effects, particularly reduction of blood flow to the inner cortex and medulla.

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Animals Dogs Hypertension Kidney Prostaglandins Prostaglandins E Prostaglandins F Renin Journal Article Research Support, U.S. Gov't, P.H.S.

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J C McGiff, D A Terragno, N A Terragno. 1978. Prostaglandins and renal function.. https://doi.org/10.1159/000401652

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