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PubMed · 708974

Hepatic osteodystrophy.

R G Long·M R Wills
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Abstract

Hepatic osteodystrophy consists of three types: osteomalacia, osteoporosis, and periosteal reaction with new bone formation. Secondary hyperparathyroidism is very rare, if it occurs at all. The cause of osteomalacia appears to be vitamin D deficiency due to a lack of vitamin D substrate. In the presence of adequate substrates, 25-OHD and dihydroxy vitamin D metabolites are formed. The vitamin D deficiency results in osteomalacia and malabsorption of calcium and phosphorus. The osteomalacia can be treated successfully with vitamin D supplements. In some patients calcium, phosphorus, and magnesium supplements may be required. The aetiology and treatment of the osteoporosis and the periosteal reactions remain obscure.

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Bone and BonesCalciumCeliac DiseaseCholestasisHepatitis, AlcoholicHumansOsteomalaciaOsteoporosisParathyroid HormonePhosphorusVitamin DVitamin D DeficiencyJournal Article

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R G Long, M R Wills. 1978. Hepatic osteodystrophy.. https://pubmed.ncbi.nlm.nih.gov/708974/

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