PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 7432738

An algorithm for determining gestational age from unconjugated estriol levels.

J E Buster·A G Freeman·C J Hobel
View original source ↗Export metadata ↓

Abstract

Between the 30th and 40th weeks of gestational age (GA), plasma unconjugated estriol (E3) concentrations plotted as a logarithmic function of GA describe a complex bimodal curve. The maximum concentrations for the first peak (GAmax1) occur at approximately 34 weeks' GA, those for the second peak (GAmax2) occur at approximately 38 weeks' GA, and a between-mode nadir occurs at 35 weeks' GA. Using the close relationship between the features of this curve and GA, a computerized algorithmic curve analysis is devised for the estimation of GA during the third trimester of pregnancy. This report describes the algorithm, its clinical application, and its preliminary performance.

Explore related subjects

ComputersEstriolFemaleGestational AgeHumansMathematicsObstetric Labor, PrematurePregnancyRiskTime FactorsJournal ArticleResearch Support, Non-U.S. Gov't

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J E Buster, A G Freeman, C J Hobel. 1980. An algorithm for determining gestational age from unconjugated estriol levels.. https://pubmed.ncbi.nlm.nih.gov/7432738/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2007

Evaluation of sites for the location of WEEE recycling plants in Spain.

As a consequence of new European legal regulations for treatment of waste electrical and electronic equipment (WEEE), recycling plants have to be installed in Spain. In this context, this contribution describes a method for ranking of Spanish municipalities according to their appropriateness for the installation of these plants. In order to rank the alternatives, the discrete multi-criteria decision method PROMETHEE (Preference Ranking Organisation METHod for Enrichment Evaluations), combined with a surveys of experts, is applied. As existing plants are located in North and East Spain, a significant concentration of top ranking municipalities can be observed in South and Central Spain. The method does not present an optimal structure of the future recycling system, but provides a selection of good alternatives for potential locations of recycling plants.

Computers↗
PubMed2007

Overview of informatics for high content screening.

With the growing use of high content screening (HCS) and analysis in drug discovery and systems biology, informatics has come to the forefront as a critical technology to effectively utilize the massive volumes of high content data and images being generated. Informatics technologies are required to transform HCS data and images into useful information and then into knowledge to drive decision making in an efficient and cost effective manner. In this chapter, we provide an overview of informatics tools and technologies for HCS, discuss some of the challenges of harnessing the huge and growing volumes of HCS data, and provide insight to help toward implementing or selecting, and utilizing a high content informatics solution to meet your organization's needs.

Computers↗