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PubMed · 7471662

Acetaminophen pharmacokinetics after overdose.

J T Slattery·J R Koup·G Levy
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Abstract

Concentrations of acetaminophen in serum and urinary excretion rates of acetaminophen glucuronide and acetaminophen sulfate were determined in a 15-year-old female who had ingested an overdose which resulted in the absorption of an estimated 9.92 g of acetaminophen. The results obtained are in reasonably good agreement with predictions of acetaminophen disposition based upon a previously developed pharmacokinetic model of capacity-limited acetaminophen elimination, but additional studies are needed to refine that model.

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AcetaminophenAdolescentHumansKidneyKineticsMetabolic Clearance RateSuicideCase ReportsJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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J T Slattery, J R Koup, G Levy. 1981. Acetaminophen pharmacokinetics after overdose.. https://doi.org/10.3109/15563658108990016

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