PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 816362

[Chagas-Mazza disease. Preliminary basic social study].

S J Kaplan·O Cuevas Báez·J Romeo Martínez
View original source ↗Export metadata ↓

Abstract

Chagas-Mazza disease is an endemic infection of chronic evolution and is essentially American. Its transmission by vinchuca in Argentine has created a medical, psychological and social problem of great and important significance. The basic, preliminary and social study carried out in a hospital unit, showed in the population attended, precarious socioenvironmental conditions during childhood and adolescence and the almost total lack of basic information on the disease. Interviews, inquests, questionnaires, group actions, team work, direct dialogues, counselling and guidance groups and the guiding to specialized institutions, constitute a synthesis of the task developed which, in its preliminary stage, showed sufficient reasons to continue the control of health during pregnancy, childbirth, puerperium and lactation.

Explore related subjects

ArgentinaChagas DiseaseFemaleHealth PlanningHumansMaleSocioeconomic FactorsEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

S J Kaplan, O Cuevas Báez, J Romeo Martínez. [Chagas-Mazza disease. Preliminary basic social study].. https://pubmed.ncbi.nlm.nih.gov/816362/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2026

Molecular diagnosis of spinal muscular atrophy: Experience in a pediatric hospital in Argentina.

Introduction. Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease caused by the loss of the SMN1 gene, with a variable clinical spectrum determined primarily by the number of copies of the SMN2 gene. The development of new therapies underscores the importance of early molecular diagnosis and genotype-phenotype characterization. Objective. To describe 27 years of experience in the molecular diagnosis of SMA at a pediatric referral hospital in Argentina and to evaluate the correlation between SMN2 copy number and the SMA types.Population and methods. A retrospective descriptive study was conducted on 1060 pediatric patients with clinically suspected SMA who were evaluated between 1997 and 2024. Molecular diagnosis was performed using PCR-RFLP and, since 2012, MLPA to determine SMN1 and SMN2 copy number. Genotype-phenotype correlation was evaluated in 260 patients with complete clinical characterization. Results. The diagnosis was confirmed in 513 patients. A homozygous deletion of the SMN1 gene was detected in 99.6% of unrelated cases. The positivity rate increased over time. A significant correlation was observed between the number of SMN2 copies and the type of SMA, with milder phenotypes associated with a higher number of copies. Conclusion. Molecular diagnosis of SMA enabled accurate and timely characterization of patients, avoiding invasive procedures and optimizing therapeutic decision-making. Genotype-phenotype correlation is a fundamental tool for prognosis and clinical management, highlighting the importance of an interdisciplinary approach.

Argentina↗
PubMed1992

[Prevalence of dental caries in elementary school children from a metropolitan area of the province of Córdoba, Argentina].

The results of a dental health epidemiologic study in primary school-children (aged 6-12) attending both public (municipal and provincial) and private schools in the city of Cordoba are described. The incidence of deciduous teeth caries was from moderate to high among the 6-year-old school-children from municipal schools but it was low in the provincial and private schools (dmf-t = 4.44, 2.31 and 1.27 respectively). Among both provincial and municipal school-children the most significant component corresponded to teeth with caries and diagnosed extraction, whereas in private school-children it corresponded to filled teeth. The absence of active caries in children was 13.6% in municipal schools, 52.2% in provincial schools and 76.9% in private schools. In 12-year-old school-children, the prevalence of caries in permanent teeth was at the same low level in all schools with a DMF-T ranging from 1.85 (municipal) to 2.59 (private). In general, the need for dental treatment was considerable in all schools. It is concluded that the dental health levels achieved by municipal and provincial schools at the age of 12 must be attributed mainly to preventive measures; should children be assisted earlier, the results would be enhanced.

Argentina↗