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PubMed · 8646863

Fluticasone propionate: safety profile.

M Johnson
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Abstract

Fluticasone propionate is a potent fluorinated corticosteroid used for the topical therapy of dermatoses and as inhalation therapy for bronchial asthma and allergic rhinitis. This agent has a good safety profile with a low propensity for systemic side effects, such as suppression of the hypothalamic-pituitary-adrenal (HPA) axis, and a low incidence of local side effects such as pruritus, burning, or skin atrophy. The pharmacologic properties of fluticasone propionate-including high lipophilicity, high selectivity and affinity for the glucocorticoid receptor, low systemic absorption, and rapid metabolism and clearance-combine to give fluticasone propionate a high therapeutic index.

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Administration, TopicalAndrostadienesAnti-Inflammatory AgentsFluticasoneGlucocorticoidsHumansSafetyJournal ArticleReview

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M Johnson. 1996. Fluticasone propionate: safety profile.. https://pubmed.ncbi.nlm.nih.gov/8646863/

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Administration, Topical↗
PubMed2007

Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study.

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