Structure and function of declarative and nondeclarative memory systems.

L R Squire; S M Zola

doi:10.1073/pnas.93.24.13515

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Structure and function of declarative and nondeclarative memory systems.

L R Squire·S M Zola

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Abstract

This article reviews recent studies of memory systems in humans and nonhuman primates. Three major conclusions from recent work are that (i) the capacity for nondeclarative (nonconscious) learning can now be studied in a broad array of tasks that assess classification learning, perceptuomotor skill learning, artificial grammar learning, and prototype abstraction; (ii) cortical areas adjacent to the hippocampal formation, including entorhinal, perirhinal, and parahippocampal cortices, are an essential part of the medial temporal lobe memory system that supports declarative (conscious) memory; and (iii) in humans, bilateral damage limited to the hippocampal formation is nevertheless sufficient to produce severe anterograde amnesia and temporally graded retrograde amnesia covering as much as 25 years.

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Amnesia Amnesia, Retrograde Animals Brain Haplorhini Hippocampus Humans Learning Memory Models, Neurological Models, Psychological Primates Temporal Lobe Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.Review

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L R Squire, S M Zola. 1996-11-26. Structure and function of declarative and nondeclarative memory systems.. https://doi.org/10.1073/pnas.93.24.13515

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