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PubMed · 9249284

Value of patch testing in atopic dermatitis.

M H el Samahy·T el-Kerdani
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Abstract

BACKGROUND: Because patients with atopic dermatitis are less prone to type IV allergies, there has been controversy regarding the role of patch testing in these patients. OBJECTIVE: The present study was conducted to evaluate the role of patch testing in atopic individuals. METHODS: One-hundred patients with hand eczema were patch tested using the standard patch test battery (HERMAL, Kurt Herrmann, Reinbek, West Germany) and the Finn chamber units. The total immunoglobulin class E (IgE) level was determined and correlated to the results of patch testing. RESULTS: Eighty-seven patients had positive patch test reactions. Among the 87 patients, 39 (44.8%) had atopic dermatitis. The most common allergens yielding positive results were nickel sulfate, 2.5%, (58.6%); potassium dichromate, 0.25% (56.3%); carba mix, 3%, (44.82%); formaldehyde, 1% in H2O, (40.22%); neomycin sulfate, 20%, (33.3%); and balsam of Peru 25%, (17.24%) respectively. Patients with atopic dermatitis were more frequently sensitive to neomycin sulfate than nonatopics. CONCLUSION: Patients with atopic dermatitis should be patch tested when indicated because they also develop contact allergic sensitization to a significant degree. Our observations indicate that patch testing with standard allergens often adds valuable information about contact sensitivity in these patients.

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AdultAllergensAnti-Bacterial AgentsBalsamsCausticsDermatitis, AtopicDitiocarbEvaluation Studies as TopicFixativesFormaldehydeGuanidinesHand DermatosesHumansHypersensitivity, DelayedImmunoglobulin EIrritantsMiddle AgedNeomycinNickelPatch TestsPotassium DichromateThiocarbamatesJournal Article

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M H el Samahy, T el-Kerdani. 1997. Value of patch testing in atopic dermatitis.. https://pubmed.ncbi.nlm.nih.gov/9249284/

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