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A study of rabbit plasma progressive antithrombinic activity during acute phase inflammatory reaction and in experimental nephrotic syndrome.

T Lebreton de Vonne·C Versavel·H Mouray
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Abstract

1. The development of the progressive antithrombinic activity in rabbit plasma as a function of the level of the two alpha-macroglobulins in two experimental pathologies: acute phase inflammatory reaction and nephrotic syndrome, were studied. 2. In the first case, the antithrombinic activity is a result of the increased biosynthesis of plasmatic antithrombins: antithrombin III, alpha 1 antitrypsin and alpha macroglobulins. 3. In the nephrotic syndrome, this activity follows the increase in the alpha M levels, the other antithrombins having been massively eliminated from the circulation in the urine.

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AnimalsAntithrombinsFibrinogenHalf-LifeInflammationMaleNephrotic SyndromeOrosomucoidRabbitsalpha-MacroglobulinsJournal ArticleResearch Support, Non-U.S. Gov't

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T Lebreton de Vonne, C Versavel, H Mouray. 1979. A study of rabbit plasma progressive antithrombinic activity during acute phase inflammatory reaction and in experimental nephrotic syndrome.. https://doi.org/10.1016/0305-0491(79)90170-6

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