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Peripheral primitive neuroectodermal tumor presenting with diffuse cutaneous involvement and 7;22 translocation.

L M Smith·R H Adams·A R Brothman·S L Vanderhooft·C M Coffin
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Abstract

We report an unusual case of peripheral primitive neuroectodermal tumor (pPNET) in an infant presenting with congenital cutaneous nodules and a t(7;22)(p21;q11.2). The biologic behavior of the tumor diverged over time from a slowly growing tumor with multiple cutaneous nodules to a more aggressive neoplasm characterized by pulmonary metastases and a soft tissue mass showing additional cytogenetic alterations.

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Chromosomes, Human, Pair 22Chromosomes, Human, Pair 7HumansInfantMaleNeuroectodermal Tumors, PrimitiveNeuroectodermal Tumors, Primitive, PeripheralSkinTranslocation, GeneticCase ReportsJournal Article

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L M Smith, R H Adams, A R Brothman, S L Vanderhooft, C M Coffin. 1998. Peripheral primitive neuroectodermal tumor presenting with diffuse cutaneous involvement and 7;22 translocation.. https://doi.org/10.1002/(sici)1096-911x(199806)30%3A6%3C357%3A%3Aaid-mpo10%3E3.0.co%3B2-f

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