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New steroidal alkaloids from Sarcococca saligna.

Atta-ur-Rahman·M I Choudhary·M R Khan·S Anjum·A Farooq·M Z Iqbal
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Abstract

Five new pregnane-type steroidal alkaloids (1-5) have been isolated from Sarcococca saligna. A combination of UV, IR, MS, and 1D and 2D NMR spectroscopic studies established their structures as salignarine A [(20S)-2beta-hydroxy-4beta-acetoxy-5alpha, 6alpha-epoxy-20-(dimethylamino)-3beta-(tigloylamino)pregnane ] (1), salignarine B [(20S)-2beta-hydroxy-20-(dimethylamino)-3beta-(tigloylamino) -pregn-5- ene] (2), salignarine C [(20S)-2beta-hydroxy-20-(dimethylamino)-3beta-(senecioylamino++ +)-pregn- 5-ene] (3), salignarine D [(20S)-20-(dimethylamino)-3beta-(senecioylamino)-5alpha-preg n-16-ene] (4), and salignarine E [(20S)-20-(dimethylamino)-3beta-(tigloylamino)-pregn-4-ene] (5), respectively.

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AlkaloidsMagnetic Resonance SpectroscopyMagnoliopsidaPakistanPhytosterolsJournal Article

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BibTeXRIS

Atta-ur-Rahman, M I Choudhary, M R Khan, S Anjum, A Farooq, M Z Iqbal. 2000. New steroidal alkaloids from Sarcococca saligna.. https://doi.org/10.1021/np990108w

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