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Parallel and nonparallel simultaneous multislice black-blood double inversion recovery techniques for vessel wall imaging.

Vitalii V Itskovich·Venkatesh Mani·Gabor Mizsei·Juan Gilberto S Aguinaldo·Daniel D Samber·Frank Macaluso·Paul Wisdom·Zahi A Fayad
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Abstract

PURPOSE: To reduce long examination times of black-blood vessel wall imaging by acquiring multiple slices simultaneously and by using parallel acquisition techniques. MATERIALS AND METHODS: DIR-rapid acquisition with relaxation enhancement (RARE) techniques imaging up to 10 simultaneous slices per acquisition with single and multiple 180 degrees -reinversion pulses were developed. A slab-selective reinversion multislice DIR-RARE sequence incorporating generalized autocalibrating partially parallel acquisitions (GRAPPA) imaging was implemented. Four-channel and eight-channel carotid coils were built to test these sequences. A total of 11 subjects were studied. Contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) efficiency factor (SEF, SNR/unit time/slice) were measured from aortic images of three healthy subjects to determine optimal MR parameters. The DIR-RARE-GRAPPA sequence was run on aortas and carotid arteries of the five remaining healthy subjects and three atherosclerotic patients with optimal parameters (acquisition times 12-21 seconds). RESULTS: SEFs of slab-selective protocols were significantly higher than those of slice-selective protocols, and SEFs of DIR-RARE-GRAPPA protocols were significantly higher than corresponding non-GRAPPA protocols (P < 0.05). CNR was not significantly different for all imaging protocols. The DIR-RARE-GRAPPA multislice sequence showed 8.35-fold time improvement vs. single-slice DIR-2RARE sequence. CONCLUSION: Future MRI atherosclerotic plaque studies can be performed in substantially shorter times using these methods.

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AdultAgedAortaAortic DiseasesArteriosclerosisCarotid ArteriesCarotid Artery DiseasesHumansMagnetic Resonance ImagingMiddle AgedSignal Processing, Computer-AssistedJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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Vitalii V Itskovich, Venkatesh Mani, Gabor Mizsei, Juan Gilberto S Aguinaldo, Daniel D Samber, Frank Macaluso, Paul Wisdom, Zahi A Fayad. 2004. Parallel and nonparallel simultaneous multislice black-blood double inversion recovery techniques for vessel wall imaging.. https://doi.org/10.1002/jmri.20022

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