Using optical coherence tomography to guide articular cartilage ablation.

Nirlep A Patel; Xingde Li; Debra L Stamper; James G Fujimoto; Mark E Brezinski

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PubMed · 15828512

Using optical coherence tomography to guide articular cartilage ablation.

Nirlep A Patel·Xingde Li·Debra L Stamper·James G Fujimoto·Mark E Brezinski

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Abstract

Current clinical imaging technologies are not capable of accurately resolving the microscopic components of articular cartilage. Optical coherence tomography (OCT) is a recently developed imaging modality analogous to ultrasound--OCT measures backreflection of infrared light instead of sound. In the study reported here, we wanted to determine the efficacy of OCT for monitoring cartilage laser ablation. Real-time imaging was conducted on bovine cartilage ablated by an argon laser in vitro. Image sequences were generated illustrating the extent of tissue degradation postablation. The images accurately correlated with histology. These results indicate that current ablation procedures could benefit from OCT guidance.

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Animals Cartilage, Articular Catheter Ablation Cattle In Vitro Techniques Tomography, Optical Coherence Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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Nirlep A Patel, Xingde Li, Debra L Stamper, James G Fujimoto, Mark E Brezinski. 2005. Using optical coherence tomography to guide articular cartilage ablation.. https://pubmed.ncbi.nlm.nih.gov/15828512/

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