Experimentally induced malakoplakia.

Z Csapó; E Kuthy; J Lantos; J Ormos

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PubMed · 166563

Experimentally induced malakoplakia.

Z Csapó·E Kuthy·J Lantos·J Ormos

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Abstract

Malakoplakia was induced experimentally by introducing large amounts of crude endotoxin-antigen comples of 075 Escherichia coli (E. coli 12797 CDC 0 group 75) into the kidneys and testes of rats. First leukocytes, then granulation tissue composed mainly of characteristic macrophages, the so-called Hansemann cells, appeared around the endotoxin-antigen mass. On the eighth day following the injection, deposition of calcium phosphate into the cytosegresomes of macrophages began and acused the formation of the Michaelis-Gutmann bodies necessary for the diagnosis of malakoplakia. The induction of the same process in humans by E coli endotoxin seems to be possible.

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Animals Antigens, Bacterial Bacillus megaterium Calcium Phosphates Endotoxins Escherichia coli Granulation Tissue Inclusion Bodies Kidney Diseases Leukocytes Macrophages Malacoplakia Male Microscopy, Electron Rats Rats, Inbred Strains Testicular Diseases Journal Article

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Z Csapó, E Kuthy, J Lantos, J Ormos. 1975. Experimentally induced malakoplakia.. https://pubmed.ncbi.nlm.nih.gov/166563/

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