[Adhesive cutaneous pharmaceutical forms].

E Gafiţanu; I Matei; O C Mungiu; M Pavelescu; I Mîndreci; I Apostol; G Ionescu

PubMed · 2636779

[Adhesive cutaneous pharmaceutical forms].

E Gafiţanu·I Matei·O C Mungiu·M Pavelescu·I Mîndreci·I Apostol·G Ionescu

Abstract

The adhesive cutaneous pharmaceutical forms aimed to local action release the drug substance in view of a dermatological, traumatological, antirheumatic, cosmetic action. Two such preparations were obtained and their stability, consistency and pH were determined. The "in vitro" tests of their bioavailability revealed the dynamics of calcium ions release according to the associations of each preparation. The bioavailability determined by evaluating the pharmacological response demonstrated the antiinflammatory action obtained by the association of calcium ions with the components extracted from poplar muds. The therapeutical efficiency of the studied preparations has proved in the treatment of some sport injuries.

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Adhesives Administration, Cutaneous Administration, Topical Animals Anti-Inflammatory Agents Athletic Injuries Biological Availability Chemistry, Pharmaceutical Drug Evaluation, Preclinical Female Humans Male Rats Rats, Inbred Strains English Abstract Journal Article

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E Gafiţanu, I Matei, O C Mungiu, M Pavelescu, I Mîndreci, I Apostol, G Ionescu. [Adhesive cutaneous pharmaceutical forms].. https://pubmed.ncbi.nlm.nih.gov/2636779/

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