PubMed · 3718271
[The "second disease" and "second nature"].
Abstract
An idea about the second disease as a metamorphosis when the phenomenon of one nature is transformed into phenomenon of the second nature is proposed. There are three stages in the development of the second disease: origin, when clinical and morphological features of initial and new nosologic forms coexist; formation-distinct groups of features of a new nosologic form which preserved a link to the first disease; separation of this new nosologic form with its typical clinical and morphological features. The second disease is metamorphosis of the first disease which develops into a new nosologic entity under the influence of exogenous or endogenous factors.
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A A Batalov, E S Belikov. 1986. [The "second disease" and "second nature"].. https://pubmed.ncbi.nlm.nih.gov/3718271/
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