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PubMed · 3740824

[Epoxy ring scission in the oleandomycin molecule during aging].

L D Antonenko·L R Davidenkov·G A Oleĭnikova·I P Serova·L Ia Severinets
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Abstract

Opening of the epoxide ring in the molecule of oleandomycin phosphate in the process of its aging was shown to be possible by the data of the analysis. Certain correlation between the "glycol" content and drug activity was detected.

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Drug StabilityDrug StorageEpoxy CompoundsEthers, CyclicMolecular ConformationOleandomycinStructure-Activity RelationshipTemperatureEnglish AbstractJournal Article

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L D Antonenko, L R Davidenkov, G A Oleĭnikova, I P Serova, L Ia Severinets. 1986. [Epoxy ring scission in the oleandomycin molecule during aging].. https://pubmed.ncbi.nlm.nih.gov/3740824/

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