[Rat postnatal development after bonafton exposure].

V A Proĭnova; G N Pershin; L F Shashkina; L V Nechushkina; E A Fedorova

PubMed · 7439376

[Rat postnatal development after bonafton exposure].

V A Proĭnova·G N Pershin·L F Shashkina·L V Nechushkina·E A Fedorova

Abstract

The first generation progeny of rats received days 10-13 of pregnancy a new antiviral drug bonaphthon (400 mg/kg) which exerts a toxic effect on females. The progeny did not show postnatal death or reduction of the life span. Moreover, no impairment of muscle work capacity, basal metabolism, cardiovascular system, peripheral blood parameters, or changes in the function of organs and systems were recorded. Morphological and functional deviations in the liver of 2-month-old progeny were unstable and got repaired by 3 months of age.

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Animals Animals, Newborn Antiviral Agents Basal Metabolism Blood Female Gestational Age Growth Kidney Liver Male Naphthoquinones Orientation Pregnancy Rats English Abstract Journal Article

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V A Proĭnova, G N Pershin, L F Shashkina, L V Nechushkina, E A Fedorova. [Rat postnatal development after bonafton exposure].. https://pubmed.ncbi.nlm.nih.gov/7439376/

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