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PubMed · 9063192

Pediatric orofacial injuries.

Abstract

Perioral injuries may have significant medical, dental and psychological consequences in children. Soft-tissue injuries are common-place, with the most common types being contusions, abrasions, lacerations and electrical and chemical burns. Each type requires specific care and follow through. Immediate intervention and treatment are important, and rapid neurologic assessment of a child before treatment helps the long-term prognosis. Children must also be screened for abuse and neglect. The common goal of treatment is to prevent infection, provide function and minimize scarring. Perioral injuries are preventable.

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BibTeXRIS

D L Rothman. 1996. Pediatric orofacial injuries.. https://pubmed.ncbi.nlm.nih.gov/9063192/

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Mitomycin C in the management of pediatric caustic esophageal strictures: a case report.

Although the incidence of caustic ingestion is declining, the management of caustic esophageal strictures remains a challenge. Mitomycin C (MMC) inhibits fibroblast proliferation and is effective in reducing scar in animal experiments. We report the case of a child with a distal esophageal stricture from lye ingestion managed with MMC. Despite repeated dilatations, at 1 year post injury, the stricture was 20% of esophageal diameter. Mitomycin C (4 microg/mL) was applied topically and circumferentially by endoscopy and repeated 4 months later. At 20 months follow-up, the child eats normally, and esophagram showed decreased stenosis (stricture was 50% of esophageal diameter). No complications were observed. Although controlled trials are required to confirm its efficacy, MMC should be considered as an adjunct in the management of caustic esophageal strictures in children.

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