Anthropomorphic breast phantoms for testing elastography systems.

Ernest L Madsen; Maritza A Hobson; Gary R Frank; Hairong Shi; Jingfeng Jiang; Timothy J Hall; Tomy Varghese; Marvin M Doyley; John B Weaver

doi:10.1016/j.ultrasmedbio.2006.02.1428

PubMed · 16785008

Anthropomorphic breast phantoms for testing elastography systems.

Ernest L Madsen·Maritza A Hobson·Gary R Frank·Hairong Shi·Jingfeng Jiang·Timothy J Hall·Tomy Varghese·Marvin M Doyley·John B Weaver

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Abstract

Two equivalent anthropomorphic breast phantoms were constructed, one for use in ultrasound elastography and the other in magnetic resonance (MR) elastography. A complete description of the manufacturing methods is provided. The materials used were oil-in-gelatin dispersions, where the volume percent oil differentiates the materials, primarily according to Young's moduli. Values of Young's moduli are in agreement with in vitro ranges for the corresponding normal and abnormal breast tissues. Ultrasound and nuclear magnetic resonance (NMR) properties are reasonably well represented. Phantoms of the type described promise to aid researchers who are developing hardware and software for elastography. Examples of ultrasound and MR elastograms of the phantoms are included to demonstrate the utility of the phantoms. Also, the level of stability of elastic properties of the component materials is quantified over a 15-month period. Such phantoms can serve as performance-assessing intermediaries between simple phantoms (consisting, for example, of homogeneous cylindrical inclusions in a homogeneous background) and a full-scale clinical trial. Thus, premature clinical trials may be avoided.

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Anthropometry Breast Breast Neoplasms Elasticity Equipment Design Female Gelatin Humans Magnetic Resonance Imaging Materials Testing Phantoms, Imaging Rheology Safflower Oil Ultrasonography, Mammary Journal Article Research Support, N.I.H., Extramural

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Ernest L Madsen, Maritza A Hobson, Gary R Frank, Hairong Shi, Jingfeng Jiang, Timothy J Hall, Tomy Varghese, Marvin M Doyley, John B Weaver. 2006. Anthropomorphic breast phantoms for testing elastography systems.. https://doi.org/10.1016/j.ultrasmedbio.2006.02.1428

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